Copper Peptides Effects on Skin
In snail skin tissues, glycosaminoglycans (GAGs) are mainly located inside granules and in the shell, and are produced on the surface as a mucous-like material. Snail glycosaminoglycan tightly unites divalent copper cations (Cu 2 ) that create copper peptides. This substance reportedly has skin rejuvenation abilities. The concentration of copper in the snail secretions is impressive.
Copper peptides have been demonstrated to be effective in just small amounts:
Copper-induced vascular endothelial growth factor expression and wound healing. Sen CK, Khanna S, Venojarvi M, Trikha P, Ellison EC, Hunt TK, Roy S. 2002 May;282(5):H1821-7.
Laboratory of Molecular Medicine, Department of Surgery, 512 Davis Heart & Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio 43210, USA.
Angiogenesis, the formation of new blood vessels, plays a vital role in wound curing. Among many recognized growth factors, the vascular endothelial growth factor (VEGF) is believed to be the most prevailing, efficacious, and long-term sign that is recognized to promote angiogenesis in wounds. Whereas the direct participation of copper in promoting angiogenesis has been known for the past two decades, the specific targets of copper activity remained uncertain.
This paper includes initial evidence, showing that inducible VEGF synthesis is related to copper production, and that the angiogenic capabilities of copper may be controlled to speed up dermal wound contraction and closure.
In physiologically normal concentrations, copper sulfate induced VEGF expression has be proven to transform human keratinocytes. Copper used some of the mechanisms utilized by hypoxia to regulate VEGF synthesis. Topical copper sulfate accelerated the closure of excisional murine dermal wounds, allowing lesions to cure themselves by secondary intention. Copper-sensitive mechanisms regulate key mediators of wound healing, like angiogenesis and extracellular matrix remodeling.
Copper-based treatment represents a feasible approach to stimulate dermal wound healing, including it among the likely components of natural skin care treatments.
Certain types of copper peptide complexes possess both tissue defense and repairing abilities. Copper has defensive and regenerative actions on several organ systems including hair follicles,bone,gastric mucosa, skin and intestinal linings. These types of copper complexes are increasingly used in cosmetic skin and hair care solutions because of their ability to trigger the regeneration of skin. You will find them among other dermatological skin renewal procedures, like chemical peels, laser resurfacing and dermabrasion, to improve post-treatment skin recovery.
The principal interest in copper peptides is in the area of reversing the effects of human aging and UV damage of the human skin. During the aging process, skin becomes thinner and tends to accumulate several skin lesions and blemishes. Within the dermis and epidermis, thin and subcutaneous fat cells diminish in quantity.
Several studies have found that the application of copper peptide creams to the human skin is even more effective in stimulating collagen development than retinoic acid or vitamin C. It also augments the thickness of the epidermis and dermis, improves cellular regeneration, reduces wrinkles and eliminates skin blemishes like blotchiness and sun damage marks.
A natural skin treatment ingredient provides solutions fast, all-naturally. Natural ingredients ensure a safe and promising skin rejuvenation process.
Published March 7th, 2008